Anti-allergic activity of some selected plants in the genus Boesenbergia and Kaempferia

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ID: 264463
2011
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Abstract
Ethanolic and water extracts from the rhizomes of eight selected Zingiberaceous plants, including Boesenbergiathorelii, Boesenbergia sp 1, Boesenbergia sp 2, Boesenbergia sp 3, Kaempferia angustifolia, Kaempferia marginata,Kaempferia rotunda and Kaempferia sp were tested for their anti-allergic activities using the rat basophilic leukemia strain2H3 (RBL-2H3) cell line. Both the ethanolic (EtOH) and water extracts of Boesenbergia thorelii exhibited the most potentanti-allergic effects against antigen-induced â-hexosaminidase release as a marker of degranulation in RBL-2H3 cells, withIC50 values of 23.0 and 26.3 g/ml, respectively. Other extracts also had some activity from Boesenbergia sp 2 (EtOH, IC50 =38.3 g/ml), Kaempferia marginata (water, IC50 = 38.4 g/ml), Boesenbergia sp 3 (EtOH, IC50 = 49.4 g/ml) and Kaempferiaangustifolia (water, IC50 = 55.6 g/ml), whereas other Boesenbergia and Kaempferia spp had little or no activity. These findingssupport the use of Boesenbergia thorelii for the treatment of allergies and allergy-related diseases.
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madaka2011antiallergicsongklanakarin Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Madaka, Fameera;Tewtrakul, Supinya;
Journal songklanakarin journal of science and technology (sjst)
Year 2011
DOI
DOI not found
URL
http://rdo.psu.ac.th/sjstweb/journal/33-3/0125-3395-33-3-301-304.pdf
Keywords
chemistry Technology (General) Technology Science (General) Science

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