ATP responsive DNA nanogels grown on biocompatible branches for anticancer drug delivery.

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ID: 26396
2019
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Abstract
We developed biocompatible ATP responsive DNA nanogels, by grafting DNA strands on carboxymethyl chitosan polymer chains, and then hybridizing with ATP aptamers to form core-shell nanogels. The DNA duplex structure could embed DOX in the G-C sequences, and realize simultaneous sol-gel transition and DOX release when suffering enrich ATP in tumor cells.
Reference Key
zhao2019atpsoft Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Zhao, Meihui;Zhang, Yu;Yuan, Shirui;Xu, Xiang;Wu, Ziheng;Wu, Zhenghong;Qi, Xiaole;
Journal Soft matter
Year 2019
DOI
10.1039/c9sm00480g
URL
Keywords Keywords not found

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