Relative importance of total versus external platelet-associated IgG

Clicks: 7
ID: 261470
1970
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #91 of 99 articles by views in blut

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
We present measurements of total platelet-associated immunoglobulin G following platelet lysis (PAIgG tot) and surface-restricted IgG (PAIgG ext) on intact, gel-filtered platelets from 36 normal human donors and 9 patients with human immunodeficiency virus (HIV) infection (CDC stages IIb–IV). For this purpose, an indirect micro ELISA technique was developed involving competition between PAIgG and solid-phase absorbed IgG for fixation of conjugated anti-human IgG antibody. In normal donors, the mean values of PAIgG tot was 8.3±7.4 (mean ±2 SD) and of PAIgG ext 4.2±4.4 fg/platelet. In HIV-infected subjects, PAIgG tot was 37.2±62.8 and PAIgG ext 17.1±23 fg/platelet. In healthy subjects the comparison of individual levels of PAIgG tot and PAIgG ext revealed a significant correlation (r:0.763; p: 0.003). These results are compared to those which have been reported in the literature. In addition, the major immunopathological mechanisms considered responsible for immune-mediated idiopathic thrombocytopenic purpura are discussed.
Reference Key
nydegger1970blutrelative Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Urs E. Nydegger;Jean-Paul Buchs;Luca Borradori;Urs E. Nydegger;Jean-Paul Buchs;Luca Borradori;
Journal blut
Year 1970
DOI
doi:10.1007/BF00320252
URL
https://link.springer.com/article/10.1007/BF00320252
Keywords
oncology hematology

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.