Directed evolution of artificial metalloenzymes for in vivo metathesis
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2016
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Abstract
An artificial metalloenzyme is compartmentalized and evolved in vivo for olefin metathesisâan archetypal organometallic reaction without equivalent in nature; the evolved metathase reveals broad substrate scope and compares favourably with commercial catalysts.
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jeschek2016naturedirected
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| Authors | Markus Jeschek;Raphael Reuter;Tillmann Heinisch;Christian Trindler;Juliane Klehr;Sven Panke;Thomas R. Ward;Markus Jeschek;Raphael Reuter;Tillmann Heinisch;Christian Trindler;Juliane Klehr;Sven Panke;Thomas R. Ward; |
| Journal | Nature |
| Year | 2016 |
| DOI |
doi:10.1038/nature19114
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