Predictors of immunologic long-term nonprogression in HIV-infected children: implications for initiating therapy

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ID: 261185
2005
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Abstract
CD8 + HLA-DR + T-lymphocyte percentage of less than 5% at 1 to 2 months of age might be predictive for ILTNP status but should not be used at this time to make treatment-deferral decisions. Immune activation in HIV-infected infants might herald more disease progression. Further study of the use of t …
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Authors Paul ME;Mao C;Charurat M;Serchuck L;Foca M;Hayani K;Handelsman EL;Diaz C;McIntosh K;Shearer WT; ;;
Journal the journal of allergy and clinical immunology
Year 2005
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/15806009
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine pregnancy prognosis research support u.s. gov't female Child Infant Comparative Study newborn P.H.S. Multicenter Study polymerase chain reaction sensitivity and specificity pregnancy complications immunophenotyping infectious / immunology disease progression roc curve flow cytometry hiv infections / immunology* viral load hiv infections / transmission infectious disease transmission vertical lymphocyte activation cd8-positive t-lymphocytes / immunology* pmid:15806009 doi:10.1016/j.jaci.2004.11.054 mary e paul charlotte mao women and infants transmission study

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