Neurodevelopmental functioning in HIV-infected infants and young children before and after the introduction of protease inhibitor-based highly active antiretroviral therapy

Clicks: 340
ID: 260648
2007
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Abstract
The suppression of systemic viral replication and subsequent substantial improvements in survival and immunologic status brought about by highly active antiretroviral therapy have been followed by limited improvements in neurodevelopmental functioning in young children. Additional longitudinal resea …
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Authors Lindsey JC;Malee KM;Brouwers P;Hughes MD; ;;
Journal pediatrics
Year 2007
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/17296781
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine treatment outcome research support female male N.I.H. Extramural age factors Child Infant Comparative Study Prospective Studies newborn preschool Evaluation Study Cohort Studies longitudinal studies antiretroviral therapy cognition / drug effects hiv infections / immunology hiv infections / drug therapy* motor activity / drug effects hiv infections / physiopathology* pmid:17296781 doi:10.1542/peds.2006-1145 jane c lindsey kathleen m malee pactg 219c study team highly active / methods child development / drug effects* hiv protease inhibitors / therapeutic use* hiv seronegativity / drug effects hiv seropositivity / drug therapy

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