the relationship between random urinary protein-to-creatinine ratio and 24-hours urine protein in diagnosis of proteinuria in mild preeclampsia

Clicks: 249
ID: 260433
2006
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Popular

Ranked #73 of 133 articles by views in 2017 ieee international conference on communication, networks and satellite, comnetsat 2017 - proceedings

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 133 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Background: The purpose of this study was to evaluate whether a random urinary protein / creatinine ratio is a clinically useful predictor of significant proteinuria (300 mg/24 hr) instead of 24- hours urine protein, among women with suspected preeclampsia. Methods: Women with suspected preeclampsia and gestational age of 20 weeks were included in a prospective study. Patients with chronic hypertension, diabetes mellitus, or preexisting renal disease were excluded. Protein/ creatinine ratio was obtained before 24-hours urine collection. Positive and negative predictive values and sensitivity and specificity of the protein/creatinine ratio for significant proteinuria (300 mg) were calculated, based on 24-hours urine total protein. Results: 100 women were evaluated totally. Mean maternal and gestational ages were 27.3 years and 33.26 weeks, respectively.73% of cases had significant proteinuria based on 24-hours urine collection. Good correlations were found between the protein/creatinine ratio in random urine samples and both the 24-hours urine protein excretion and the 24- hours urine protein/creatinine ratio in patients with mild preeclampsia (r=0.484, P<0.0001, and r=0.345, P<0.0001, respectively) .Receiver operator characteristic (ROC) analysis revealed an area under the curve of 0.944. The best cutoff value was of >0.18 which yields a sensitivity of 86.3%, a specificity of 100%, with a positive predictive value of 100%, and a negative predictive value of 73%. Conclusion: The random urinary protein –to- creatinine (P: C) ratio is strongly associated with the 24-hours total protein excretion. A cutoff value of > 0.18 is a good predictor of significant proteinuria .P: C ratio could replace the 24- hours urine collection as a simpler, faster, and more accurate method for the diagnosis of significant proteinuria. Key words: Preeclampsia, significant proteinuria, protein / creatinine (P: C) ratio, 24- hours urine total protein level
Reference Key
taherian2006journalthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors AA Taherian, S Dehbashi, M Baghban
Are you one of these authors? Claim your profile
Journal 2017 ieee international conference on communication, networks and satellite, comnetsat 2017 - proceedings
Year 2006
DOI
DOI not found
URL
http://journals.mui.ac.ir/jrms/article/view/93
Keywords
Medicine

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.