subcorneal pustular dermatosis in childhood: a case report and review of the literature

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ID: 259782
2013
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Abstract
Subcorneal pustular dermatosis (SCPD, also known as Sneddon-Wilkinson disease) is a rare, benign, chronic, sterile pustular eruption which usually develops in middle-age or elderly women; it is rarely seen in childhood and adolescence. The primary lesions are pea-sized pustules classically described as half-pustular, half-clear flaccid blisters. Histologically the most important feature is a subcorneal accumulation of neutrophils with the absence of spongiosis or acantholysis, although acantholysis may be reported in older lesions. In this paper we present the case of a 7-year-old boy diagnosed with SCPD based on the characteristic clinical and histological features. Dapsone has been successfully used in the treatment of the disease.
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Authors ;Massimiliano Scalvenzi;Franco Palmisano;Maria Carmela Annunziata;Ernesto Mezza;Immacolata Cozzolino;Claudia Costa
Journal diogenes
Year 2013
DOI
10.1155/2013/424797
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