tratamento da esquistossomose com oxamniquine (xarope) em crianças
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ID: 259522
1975
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Abstract
Foram tratados pela oxamniquine, sob a forma de xarope, 75 esquistossomôticos. com idade de 3 a 12 anos, distribuídos uniformente por quatro grupos, utilizando-se os esquemas de 15, 20 e 25 mg por quilo de peso corporal, em dose única e 20mg subdivididos em duas doses com intervalo de quatro horas. O controle de cura foi feito com cinco exames de fezes no período de seis meses. A dose de 20 mg, mesmo subdividida, apresentou os melhores resultados com 94,7% de cura e boa tolerabilidade. A dose de 15 mg, embora sendo a melhor tolerada, deu somente 62,5 % de cura. A dose de 25 mg foi a que apresentou pior tolerância. A eficácia das doses de oxamniquine aumenta com a idade das , crianças tratadas.
75 patients aged 3 to 12 years were divided equally into 4 groups and treated with oxamniquine syrup in doses of 15, 20 and 25 mg per kg/body weight given as a single dose and 20 mg divided into two doses with an interval of 4 hours between doses. The control of cure was 5 faecal examinations performed consecutively during a period of six months. The divided dose of 20 mg gave very good results with 94.7% cure and good tolerance. The 15 mg dose although well tolerated gave only 62.5% cure. A 25 mg single dose was poorly tolerated. The efficacy of the dose of oxamniquine rose with the age of child treated.
75 patients aged 3 to 12 years were divided equally into 4 groups and treated with oxamniquine syrup in doses of 15, 20 and 25 mg per kg/body weight given as a single dose and 20 mg divided into two doses with an interval of 4 hours between doses. The control of cure was 5 faecal examinations performed consecutively during a period of six months. The divided dose of 20 mg gave very good results with 94.7% cure and good tolerance. The 15 mg dose although well tolerated gave only 62.5% cure. A 25 mg single dose was poorly tolerated. The efficacy of the dose of oxamniquine rose with the age of child treated.
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| Authors | ;J. C. Bina;A. Prata |
| Journal | mobile information systems |
| Year | 1975 |
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