maternal methyltetrahydrofolate reductase gene mutation in patients with missed abortions

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ID: 259462
2018
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Abstract
Background: Missed abortions are a common problem, often caused by thrombophilia in both recurring and non-recurring cases. Aim: To determine whether the presence of a mutation in the methyltetrahydrofolate reductase (Mthfr) gene correlates with missed abortions. Patients and methods: We selected two hundred patients for this study in two groups: the study group, which consisted of one hundred patients with a history of missed abortion; and the control group, which consisted of one hundred patients with no history of missed abortion. Results: Of the 200 patients, mutations in Mthfr were only found in forty-four patients—thirty-four from the study group and ten from the control group. Conclusions: Mthfr gene mutation is a common cause of both recurring and non-recurring missed abortions.
Reference Key
md2018journalmaternal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Helmy A. Rady, MD
Journal social inclusion
Year 2018
DOI
10.1016/j.jtumed.2017.04.004
URL
http://www.sciencedirect.com/science/article/pii/S1658361217300598
Keywords
recurrent miscarriage habitual abortion

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