spinal antinociceptive action of amiloride and its interaction with tizanidine in the rat formalin test
Clicks: 114
ID: 259191
2015
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Abstract
BACKGROUND: Amiloride has been reported to produce a wide variety of actions, thereby affecting several ionic channels and a multitude of receptors and enzymes. Intrathecal α2-adrenergic receptor agonists produce pronounced analgesia, and amiloride modulates α2-adrenergic receptor agonist binding and function, acting via the allosteric site on the α2A-adrenergic receptor.
| Reference Key |
ouyang2015painspinal
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|---|---|
| Authors | ;Handong Ouyang;Peizong Wang;Wan Huang;Qiang Li;Bilin Nie;Weian Zeng |
| Journal | chemistryselect |
| Year | 2015 |
| DOI |
10.1155/2015/902914
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| URL | |
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