polarographic analysis of structurally modified paracetamol
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ID: 258965
2010
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Abstract
Paracetamol is an analgesic drug. Its potency may be increased by modifying the drug by way of molecular modification. In the present study the drug has been modified by its complex formation with methanol and other organic compounds. The drug organic compound interaction has been studied using differential pulse polarography and direct current polarography. In Britton Robinson buffer as supporting electrolyte of pH 7.2±0.1, paracetamol produced a well defined peak at -1.18v and it’s modified forms at relatively higher negative value. The change in peak potential and lowering in peak height indicating drug organic compound complex formation.
| Reference Key |
choure2010e-journalpolarographic
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|---|---|
| Authors | ;Rakesh Choure;K. S. Pitre |
| Journal | Journal of pharmaceutical and biomedical analysis |
| Year | 2010 |
| DOI |
10.1155/2010/418279
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| URL | |
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