the erythrocyte cytoskeleton protein 4.2 is not demonstrable in several mammalian species

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ID: 258082
1999
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Abstract
Erythrocyte membrane proteins from 44 representative mammals were studied. Protein 4.2 was not detected in guinea pigs (Cavia porcellus) (N = 14), Southern Brazilian swamp large rats (Myocastor coypus) (N = 2), cutias (Dasyprocta sp) (N = 4), and horses (Equus caballus) (N = 13). These animals also presented high ankyrin concentrations except for the horse which did not exhibit a sharp band, although minor components located between proteins 2 and 3 could account for the ankyrin family. The rodents studied did present band 6, which was not detectable in other common rodents such as white rats (Rattus norvegicus) (N = 9) and mice (Mus musculus) (N = 12). Since the absence of protein 4.2 does not disrupt the cytoskeleton membrane, we suggest that it is not an essential protein. Its absence may be compensated physiologically by the higher ankyrin concentration observed.
Reference Key
guerra-shinohara1999brazilianthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;E.M. Guerra-Shinohara;O.C. de O. Barretto
Journal Free radical biology & medicine
Year 1999
DOI
10.1590/S0100-879X1999000600003
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000600003
Keywords
2 mammalsmedicine (general)biology (general)

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