the prevention of ischemic stroke with antithrombotic drugs

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ID: 258063
2012
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Abstract
Current antithrombotic drugs reduce the risk of stroke, heart attack and death from vascular causes by 25 % in patients with cerebral ischemic events resulting from disease of small or large cerebral arteries. In the primary prevention, Acetylsalicylic acid (ASA) reduces the risk of stroke by 19 % in women but not in men. In patients with nonvalvular atrial fibrillation the risk of stroke treating with ASA is reduced by 20 %. Oral anticoagulants significantly reducestroke risk due to nonvalvular atrial fibrillation by 65–70 % compared with placebo and by 40 % compared with ASA alone. At the same time they cause more major bleedings. Recently studied new antiplatelet drugs and anticoagulants might alter the current course of stroke prevention treatment. Research is also needed on the benefits and risks of combination antiplatelets and anticoagulants in patients with non valvular atrial fibrillation in combination with arterial cerebral disease.
Reference Key
perko2012zdravnikithe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Denis Perko;Marjan Zaletel
Journal planta medica
Year 2012
DOI
DOI not found
URL
http://vestnik.szd.si/index.php/ZdravVest/article/view/561
Keywords
Medicine

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