efficacy of metformin and atorvastatin in correction of indices of carbohydrate and lipid metabolism in patients with type 2 diabetes mellitus

Clicks: 200
ID: 258036
2013
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Abstract
This paper presents the results of metformin and atorvastatin use in patients with type 2 diabetes mellitus (DM). 25 patients with type 2 diabetes mellitus (DM) had been observed. Patients were treated with metformin and atorvastatin during 12 weeks. It is shown that use of metformin and atorvastatin significantly improves the indices of carbohydrate and lipid metabolism, reduces hyperinsulinemia and concomitant insulin resistance. Use of metformin and atorvastatin reduces daytime blood pressure level, improves myocardial diastolic function, reduces microalbuminuria. Among subjects with diastolic dysfunction, in 56.3 % patients the improvement of diastolic function was marked, its normalization has been observed in 18.8 % patients. During treatment with metformin and atorvastatin weight loss with the redistribution of fat deposits toward decrease of visceral obesity had been noted.
Reference Key
pankiv2013mnarodnijefficacy Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;V.I. Pankiv
Journal Macromolecular rapid communications
Year 2013
DOI
10.22141/2224-0721.2.50.2013.84267
URL
http://iej.zaslavsky.com.ua/article/view/84267
Keywords
metformin type 2 diabetes mellitus clinical endocrinology

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