estradiol meets notch signaling in developing neurons
Clicks: 283
ID: 257531
2011
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Popular Article
30.0
/100
283 views
61 readers
AI Quality Assessment
Not analyzed
Readership in this journal
PopularRanked #112 of 262 articles by views in aip advances
Most read
Least read
Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 262 in total.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
The transmembrane receptor Notch, a master developmental regulator, controls gliogenesis, neurogenesis and neurite development in the nervous system. Estradiol, acting as a hormonal signal or as a neurosteroid, also regulates these developmental processes. Here we review recent evidence indicating that estradiol and Notch signaling interact in developing hippocampal neurons by a mechanism involving the putative membrane receptor G protein-coupled receptor 30. This interaction is relevant for the control of neuronal differentiation, since the downregulation of Notch signaling by estradiol results in the upregulation of neurogenin 3, which in turn promotes dendritogenesis.
| Reference Key |
earevalo2011frontiersestradiol
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | ;Maria-Angeles eArevalo;Isabel eRuiz-Palmero;Julia eSimon-Areces;Estefania eAcaz-Fonseca;Iñigo eAzcoitia;Luis Miguel Garcia-Segura |
| Journal | aip advances |
| Year | 2011 |
| DOI |
10.3389/fendo.2011.00021
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.