synthesis of some new 4,5-substituted-4h-1,2,4-triazole-3-thiol derivatives

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ID: 255995
2004
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Abstract
In this study appropriate hydrazide compounds, furan-2-carboxylic acidhydrazide (1) and phenylacetic acid hydrazide (2) were converted into 1,4-substitutedthiosemicarbazides 4a-e and 5a-e and 4-amino-5-(furan-2-yl or benzyl)-4H-1,2,4-triazole-3-thiols 7 and 10. The 1,4-substituted thiosemicarbazides were then converted into5-(furan-2-yl or benzyl)-4-(aryl)-4H-1,2,4-triazole-3-thiols 8a-e and 9a-e. In addition, theazomethines 11a-d and 12a-d were prepared from the corresponding arylaldehydes and the4-amino-5-(furan-2-yl or benzyl)-4H-1,2,4-triazole-3-thiols 7 and 10. The structures of allthe synthesized compounds were confirmed by elemental analyses, IR, 1H-NMR and13 C-NMR spectra.
Reference Key
demirda2004moleculessynthesis Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;A. Demirdağ;A. Cansız;M. Koparır
Journal Journal of ethnopharmacology
Year 2004
DOI
10.3390/90400204
URL
http://www.mdpi.com/1420-3049/9/4/204/
Keywords
2 Organic Chemistry 4-triazole-3-thiols

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