the photobiology of lutein and zeaxanthin in the eye

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ID: 255797
2015
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Abstract
Lutein and zeaxanthin are antioxidants found in the human retina and macula. Recent clinical trials have determined that age- and diet-related loss of lutein and zeaxanthin enhances phototoxic damage to the human eye and that supplementation of these carotenoids has a protective effect against photoinduced damage to the lens and the retina. Two of the major mechanisms of protection offered by lutein and zeaxanthin against age-related blue light damage are the quenching of singlet oxygen and other reactive oxygen species and the absorption of blue light. Determining the specific reactive intermediate(s) produced by a particular phototoxic ocular chromophore not only defines the mechanism of toxicity but can also later be used as a tool to prevent damage.
Reference Key
roberts2015journalthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Joan E. Roberts;Jessica Dennison
Journal chemical reviews
Year 2015
DOI
10.1155/2015/687173
URL
http://dx.doi.org/10.1155/2015/687173
Keywords
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