the photobiology of lutein and zeaxanthin in the eye
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2015
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Abstract
Lutein and zeaxanthin are antioxidants found in the human retina and macula. Recent clinical trials have determined that age- and diet-related loss of lutein and zeaxanthin enhances phototoxic damage to the human eye and that supplementation of these carotenoids has a protective effect against photoinduced damage to the lens and the retina. Two of the major mechanisms of protection offered by lutein and zeaxanthin against age-related blue light damage are the quenching of singlet oxygen and other reactive oxygen species and the absorption of blue light. Determining the specific reactive intermediate(s) produced by a particular phototoxic ocular chromophore not only defines the mechanism of toxicity but can also later be used as a tool to prevent damage.
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roberts2015journalthe
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| Authors | ;Joan E. Roberts;Jessica Dennison |
| Journal | chemical reviews |
| Year | 2015 |
| DOI |
10.1155/2015/687173
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