antifungal susceptibility testing of fusarium: a practical approach

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ID: 255776
2017
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Abstract
In vitro susceptibility testing of Fusarium is becoming increasingly important because of frequency and diversity of infections and because resistance profiles are species-specific. Reference methods for antifungal susceptibility testing (AFST) are those of Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility (EUCAST), but breakpoints (BPs) have not yet been established. One of the problems is that phylogenetic distances between Fusarium species are much smaller than between species of, e.g., Candida. Epidemiological cutoff values (ECVs) for some Fusarium species have been determined in order to differentiate wild-type from non-wild-type isolates. In clinical routine, commercially available assays such as Etest, Sensititre or others provide essential agreement with reference methods. Our objective is to summarize antifungal susceptibility testing of Fusarium genus in the clinical laboratory: how to do it, when to do it, and how to interpret it.
Reference Key
al-hatmi2017journalantifungal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Abdullah M. S. Al-Hatmi;Ilse Curfs-Breuker;G. Sybren de Hoog;Jacques F. Meis;Paul E. Verweij
Journal planta med
Year 2017
DOI
10.3390/jof3020019
URL
http://www.mdpi.com/2309-608X/3/2/19
Keywords
fusarium clinical laboratory

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