doença de mucha-habermann úlceronecrótica febril em adulto com boa resposta à corticoterapia oral febrile ulceronecrotic mucha-habermann disease in adult patient successfully treated with systemic corticosteroid

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ID: 255356
2010
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Abstract
A doença de Mucha-Habermann ulceronecrótica febril (FUMHD) é uma variante clínica rara da pitiríase liquenoide variceliforme aguda (PLEVA). Tem etiologia incerta e é caracterizada por lesões úlceronecróticas, associadas a sintomas sistêmicos. Relata-se um caso de paciente masculino, com início agudo de lesões máculo-papulares, vesicobolhosas e úlceronecróticas, associadas à febre alta e mialgia. Tratado com prednisona 0,5 mg/kg/dia, obteve-se excelente resposta terapêutica. A FUMHD é uma variante severa da PLEVA, cujo diagnóstico é clínico e histopatológico. Vários tratamentos são descritos, tais como: metrotexate, corticoesteroides, PUVA, mas nenhum foi estabelecido.
The Febrile Ulceronecrotic Mucha-Habermann (FUMHD) disease is a rare variant of pityriasis lichenoides et varioliformis acuta (PLEVA). Its etiology still remains unknown and it is characterized by a sudden onset of ulceronecrotic skin lesions associated with systemic symptons. It is reported here the case of a male patient with a sudden and acute evolution of macules and papules, ulceronecrotic and vesicle-bullous lesions associated with systemic symptons. The patient was treated with prednisone 0,5 mg/kg/day with a dramatic response. The FUMHD is a severe variant of PLEVA and its diagnosis is clinical and histopathological. Many treatments such as methotrexate, corticosteroids and PUVA have been described .However, none of them has been settled.
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Authors ;Priscila Wolf Nassif;Deise Aparecida Santos Godoy;Sadamitsu Nakandakari;Cinthia Janine Meira Alves;Cleverson Teixeira Soares
Journal Theriogenology
Year 2010
DOI
10.1590/S0365-05962010000600018
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962010000600018
Keywords
adrenal cortex hormones vasculitisdermatology

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