research progress of transfering mitochondria application in nanotubes in treatment of acute lung injury sepsis

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ID: 255125
2017
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Abstract
Acute lung injury (ALI) is a common complication of sepsis with characteristics of acute onset, rapid change in the disease and high mortality. Since current clinical treatment can only alleviate the unfavorable condition to a certain extent but cure, we urgently need to find an effective treatment. Most scholars believe that sepsis-induced ALI is associated with extensive mitochondrial damage. In recent years, a widely studied pluripotent stem cell that is mesenchymal stem cell has been proved to alleviate and treat sepsis-induced ALI by transporting mitochondria via nanotubes in a microtubule-dependent manner. Research progress in this field will be reviewed in this study.
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Authors ;Jin Qian;Dong-Mei Sun;Qi-Feng Huang;Xiao-Ran Liu
Journal journal of education, health and sport
Year 2017
DOI
10.4103/2221-6189.221286
URL
http://www.jadweb.org/article.asp?issn=2221-6189;year=2017;volume=6;issue=6;spage=241;epage=244;aulast=Qian
Keywords
mitochondria mesenchymal stem cells sepsis nanotubes critical care first aid intensive care acute lung injurymedical emergencies

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