vitamin a deficiency after gastric bypass surgery: an underreported postoperative complication
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2011
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Abstract
Introduction. Few data are available on vitamin A deficiency in the gastric bypass population.
Methods. We performed a retrospective chart review of gastric bypass patients (n=69, 74% female). The relationship between serum vitamin A concentration and markers of protein metabolism at 6-weeks and 1-year post-operative were assessed.
Results. The average weight loss at 6-weeks and 1-year following surgery was 20.1±9.1 kg and 44.1±17.1 kg, respectively. At 6 weeks and 1 year after surgery, 35% and 18% of patients were vitamin A deficient, (<325 mcg/L). Similarly, 34% and 19% had low pre-albumin levels (<18 mg/dL), at these time intervals. Vitamin A directly correlated with pre-albumin levels at 6 weeks (r=0.67, P<0.001) and 1-year (r=0.67, P<0.0001). There was no correlation between the roux limb length measurement and pre-albumin or vitamin A serum concentrations at these post-operative follow-ups. Vitamin A levels and markers of liver function testing were also unrelated.
Conclusion. Vitamin A deficiency is common after bariatric surgery and is associated with a low serum concentration of pre-albumin. This fat-soluble vitamin should be measured in patients who have undergone gastric bypass surgery and deficiency should be suspected in those with evidence of protein-calorie malnutrition.
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| Reference Key |
zalesin2011journalvitamin
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|---|---|
| Authors | ;Kerstyn C. Zalesin;Wendy M. Miller;Barry Franklin;Dharani Mudugal;Avdesh Rao Buragadda;Judith Boura;Katherine Nori-Janosz;David L. Chengelis;Kevin R. Krause;Peter A. McCullough |
| Journal | chinese chemical letters |
| Year | 2011 |
| DOI |
10.1155/2011/760695
|
| URL | |
| Keywords |
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