selection criteria for the radical treatment of locally advanced rectal cancer

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ID: 253753
2011
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Abstract
There are over 14,000 newly diagnosed rectal cancers per year in the United Kingdom of which between 50 and 64 percent are locally advanced (T3/T4) at presentation. Pelvic exenterative surgery was first described by Brunschwig in 1948 for advanced cervical cancer, but early series reported high morbidity and mortality. This approach was later applied to advanced primary rectal carcinomas with contemporary series reporting 5-year survival rates between 32 and 66 percent and to recurrent rectal carcinoma with survival rates of 22–42%. The Swansea Pelvic Oncology Group was established in 1999 and is involved in the assessment and management of advanced pelvic malignancies referred both regionally and UK wide. This paper will set out the selection, assessment, preparation, surgery, and outcomes from pelvic exenterative surgery for locally advanced primary rectal carcinomas.
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davies2011internationalselection Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Mansel Leigh Davies;Dean Harris;Mark Davies;Malcolm Lucas;Peter Drew;John Beynon
Journal Langmuir : the ACS journal of surfaces and colloids
Year 2011
DOI
10.1155/2011/678506
URL
http://dx.doi.org/10.1155/2011/678506
Keywords
neoplasms Oncology including cancer and carcinogens tumors

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