an alkaloid and a steroid from the endophytic fungus aspergillus fumigatus

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ID: 253632
2015
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Abstract
Two new compounds, fumitremorgin 12-methoxy-13-[5'-hydroxy-2'-(1''-hydroxy-3''-methoxy-5''-methylbenzoyl)-3'-methoxy]benzoic acid methyl ester (fumitremorgin D, 1) and 4,8,10,14-tetramethyl-6-acetoxy-14-[16-acetoxy-19-(20,21-dimethyl)-18-ene]-phenanthrene-1-ene-3,7-dione (2) were isolated from the cultured endophytic isolated fungus Aspergillus fumigatus, together with fourteen known compounds. Their structures were elucidated by 1-D and 2-D NMR analyses. The cytotoxicity profile of the compound against the human hepatocellular carcinoma cell line HepG2 was evaluated by MTT antiproliferative assays.
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liang2015moleculesan Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Zizhen Liang;Tiantian Zhang;Xiaoqian Zhang;Jia Zhang;Changqi Zhao
Journal Journal of ethnopharmacology
Year 2015
DOI
10.3390/molecules20011424
URL
http://www.mdpi.com/1420-3049/20/1/1424
Keywords
steroid cytotoxicityorganic chemistry indolediketopiperazine alkaloids

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