disseminated streptococcus anginosus infection with empyema thoracis in a patient with sarcoma

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ID: 250626
2006
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Ranked #114 of 246 articles by views in Bioorganic & medicinal chemistry letters

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Abstract
Streptococcus anginosus is a member of the normal flora of the oral cavity and a pathogen of thoracic infection. However, disseminated infection that was identified from different body fluids at the same time has never been reported. We report a 52-year-old man with advanced pulmonary sarcoma who developed neutropenia, bronchopleural fistula and thoracic empyema after chemotherapy. Viridans group Streptococcus was isolated from both empyema and urine, which was confirmed as S. anginosus according to the biochemical reaction profiles and 16S rRNA gene sequencing results. The patient recovered uneventfully after tube drainage and treatment with imipenem. Disseminated S. anginosus infection should be considered as a possible pathogen in immunocompromised patients with empyema and can be rapidly identified by 16S rRNA gene sequencing.
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chuang2006journaldisseminated Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Yu-Min Chuang;Po-Ren Hsueh;Peilin Lee
Journal Bioorganic & medicinal chemistry letters
Year 2006
DOI
10.1016/S0929-6646(09)60205-9
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