cardio-ankle vascular index and indices of diabetic polyneuropathy in patients with type 2 diabetes

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ID: 249538
2017
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Abstract
The cardio-ankle vascular index (CAVI) is used to test vascular function and is an arterial stiffness marker and potential predictor of cardiovascular events. This study aimed to analyze the relation between objective indices of diabetic polyneuropathy (DPN) and the CAVI. One hundred sixty-six patients with type 2 diabetes mellitus were included in this study. We used nerve conduction studies (NCSs) and the coefficient of variation of the R-R interval to evaluate DPN. We estimated arteriosclerosis by the CAVI. Simple and multiple linear regression analyses were performed between neuropathy indices and the CAVI. In univariate analysis, the CAVI showed significant associations with sural sensory nerve conduction velocity and median F-wave conduction velocity. Multiple linear regression analysis for the CAVI showed that sural nerve conduction velocity and median F-wave conduction velocity were significant explanatory variables second only to age. In multiple linear regression analysis for sural nerve conduction velocity among neuropathy indices, the CAVI remained the most significant explanatory variable. In multiple linear regression analysis for median nerve F-wave conduction velocity among neuropathy indices, the CAVI remained the second most significant explanatory variable following HbA1c. These results suggest a close relationship between macroangiopathy and DPN.
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ando2017journalcardio-ankle Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Akihiko Ando;Michiaki Miyamoto;Kazuhiko Kotani;Kenta Okada;Shoichiro Nagasaka;Shun Ishibashi
Journal applied computer science
Year 2017
DOI
10.1155/2017/2810914
URL
http://dx.doi.org/10.1155/2017/2810914
Keywords
clinical endocrinology diseases of the endocrine glands

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