síndrome de guillain-barré em associação temporal com a vacina influenza a guillain-barré syndrome in temporal association with influenza a vaccine
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Abstract
OBJECTIVE: To report a case of Guillain-Barré syndrome following influenza A (H1N1) 2009 vaccine. CASE DESCRIPTION: A four-year-old boy presented right thigh pain and ascending muscular weakness 15 days after the second dose of influenza A (H1N1) 2009 vaccine. The neurological examination revealed tetraparesis and areflexia. Electroneuromyography showed lower velocity and conduction blockage with small secondary axonal loss. Treated with intravenous immunoglobulin, the patient reached a plateau in the 4th day, followed by progressive muscular strength improvement. COMMENTS: The employment of large-scale influenza A (H1N1) 2009 vaccination and the preliminary reports from the American Surveillance Program suggest a significant association between Guillain-Barré syndrome and influenza A H1N1 2009 vaccination. All suspected cases of this association should be published for further evaluation. Vaccination remains the most effective method to prevent serious illness and death related to influenza.
| Reference Key |
ferrarini2011revistasndrome
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| Authors | ;Maria Aparecida G Ferrarini;Mônica Ayres A Scattolin;Marcelo Masruha Rodrigues;Maura Helena F Resende;Isabel Cristina L. dos Santos;Antônio Vladir Iazzetti |
| Journal | proceedings of the acm symposium on applied computing |
| Year | 2011 |
| DOI |
10.1590/S0103-05822011000400033
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