the use of plasma-derived complement c1-esterase inhibitor concentrate (berinert®) in the treatment of angiotensin converting enzyme-inhibitor related angioedema

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ID: 248588
2016
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Abstract
Angioedema of the upper airways is a severe and potentially life-threatening condition. The incidence has been increasing in the past two decades, primarily due to pharmaceuticals influencing the generation or degradation of the vasoactive molecule bradykinin. Plasma-derived C1-esterase inhibitor concentrate is a well-established treatment option of hereditary and acquired complement C1-esterase inhibitor deficiency, which are also mediated by an increased level of bradykinin resulting in recurrent angioedema. We here present a case of severe angiotensin converting enzyme-inhibitor related angioedema (ACEi-AE) of the hypopharynx that completely resolved rapidly after the infusion of plasma-derived C1-inhibitor concentrate adding to the sparse reports in the existing literature.
Reference Key
hermanrud2016casethe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Thorbjørn Hermanrud;Nicolaj Duus;Anette Bygum;Eva Rye Rasmussen
Journal Ecology letters
Year 2016
DOI
10.1155/2016/3930923
URL
http://dx.doi.org/10.1155/2016/3930923
Keywords
critical care first aid intensive care medical emergencies

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