syntheses, characterization and antimicrobial evaluation of some 1, 3, 5-trisubustituted pyrazole derivatives

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ID: 248513
2010
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Abstract
A series of 1, 3, 5-trisubustituted pyrazole derivatives were synthesized and screened for antimicrobial activity. The compounds (2j-o) were evaluated against two gram-positive and two gram-negative bacteria and one fungus, at concentrations of 10 µg/mL and 50 µg/mL. The compounds were founds to be inactive against P. aeruginosa and A. niger but exhibited moderate activity against B. subtilis, E. coli and S. aureus. It can be concluded that the newly synthesized compounds possess promising antimicrobial activity.
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gautam2010e-journalsyntheses, Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Vertika Gautam;Viney Chawla;Pankaj k. Sonar;Shailendra K. Saraf
Journal Journal of pharmaceutical and biomedical analysis
Year 2010
DOI
10.1155/2010/947215
URL
http://dx.doi.org/10.1155/2010/947215
Keywords
chemistry

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