alteraciones electrocardiográficas y factores de riesgo cardiovascular en pacientes con diabetes tipo 2 electrocardiographic abnormalities and cardiovascular risk factors in patients with type 2 diabetes
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ID: 246668
1999
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Abstract
Objetivo. Determinar cuáles son las alteraciones del ritmo y la conducción cardiaca más frecuentes en pacientes con diabetes tipo 2 sin cardiopatía previa y establecer su asociación con los factores de riesgo cardiovascular. Material y métodos. Se incluyeron pacientes con diabetes tipo 2 sin presencia o antecedentes de cardiopatía. Se determinaron los factores de riesgo cardiovascular, el índice de masa corporal y los niveles séricos de glucosa, colesterol y triglicéridos. Se registró electrocardiograma convencional en reposo. La asociación de las variables en estudio con la ocurrencia de arritmias se calculó con un modelo de análisis multivariado ajustado por sexo. Resultados. Se integraron 199 pacientes: 113 mujeres (56.8%) y 86 hombres (43.2%), y se identificó algún tipo de alteración electrocardiográfica en 29.1% de los sujetos. El hemibloqueo fascicular anterior (HFA) y el bloqueo completo de rama derecha del Haz de His (BRDHH), constituyeron 75.9% de las alteraciones identificadas. Los pacientes con trastornos del ritmo y la conducción tienen niveles más elevados de colesterol y triglicéridos. La aparición de arritmias se relaciona directamente con el incremento de la edad (r= 0.75, p= 0.01). En el análisis multivariado ajustado por sexo la hipercolesterolemia y la edad se asociaron significativamente con las alteraciones del ritmo y la conducción: RM 1.5, IC95% 1.1-4.6, p< 0.05 y RM 1.3, IC95% 1.0-5.2, p< 0.05, respectivamente. Conclusiones. Las alteraciones del ritmo y la conducción cardiaca más frecuentes en la diabetes tipo 2 son el HFA y el BRDHH; la hipercolesterolemia y la edad son los factores asociados a su presencia.
Objective. To determine the most frequent alterations in rhythm and cardiac conduction in patients with type 2 diabetes without previous cardiopathy, and to establish the association of this disease with cardiovascular risk factors. Material and methods. Subjects with type 2 diabetes, without cardiopathy antecedents were included in the study. Cardiovascular risk factors, body mass index and serum glucose, cholesterol and trygliceride levels were determined. A resting electrocardiogram was recorded. The association between the variables under study and arrhythmia was calculated with a multivariate analysis adjusted by sex. Results. A total of 199 patients were included: 113 women (56.8%) and 86 men (43.2%). Arrhythmia was registered in 29.1% of the subjects. Anterior hemiblock (AH) and right bundle branch block (RBBB) constituted 75.9% of the identified alterations. Patients with arrhythmia and conduction disorders have higher levels of cholesterol and triglycerides. Appearance of arrhythmia is directly related to aging (r= 0.75, p= 0.01). The multivariate analysis adjusted by sex revealed that hypercholesterolemia and aging are significantly associated with arrhythmia and conduction alterations: OR 1.5, CI 95%, 1.1-4.6, p< 0.05 and OR 1.3, CI 95% 1.0-5.2, p< 0.05, respectively. Conclusions. The most frequent arrhythmia and conduction disorders in type 2 diabetes are AH and RBBB. Hypercholesterolemia and aging are the strongest and most frequent factors associated to the presence of this disease.
Objective. To determine the most frequent alterations in rhythm and cardiac conduction in patients with type 2 diabetes without previous cardiopathy, and to establish the association of this disease with cardiovascular risk factors. Material and methods. Subjects with type 2 diabetes, without cardiopathy antecedents were included in the study. Cardiovascular risk factors, body mass index and serum glucose, cholesterol and trygliceride levels were determined. A resting electrocardiogram was recorded. The association between the variables under study and arrhythmia was calculated with a multivariate analysis adjusted by sex. Results. A total of 199 patients were included: 113 women (56.8%) and 86 men (43.2%). Arrhythmia was registered in 29.1% of the subjects. Anterior hemiblock (AH) and right bundle branch block (RBBB) constituted 75.9% of the identified alterations. Patients with arrhythmia and conduction disorders have higher levels of cholesterol and triglycerides. Appearance of arrhythmia is directly related to aging (r= 0.75, p= 0.01). The multivariate analysis adjusted by sex revealed that hypercholesterolemia and aging are significantly associated with arrhythmia and conduction alterations: OR 1.5, CI 95%, 1.1-4.6, p< 0.05 and OR 1.3, CI 95% 1.0-5.2, p< 0.05, respectively. Conclusions. The most frequent arrhythmia and conduction disorders in type 2 diabetes are AH and RBBB. Hypercholesterolemia and aging are the strongest and most frequent factors associated to the presence of this disease.
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| Authors | ;Martha Rodríguez-Morán;Fernando Guerrero-Romero |
| Journal | journal of anatomy |
| Year | 1999 |
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