is weekly supplementation of vitamin d favorable for treatment of osteoporosis in postmenopausal women?
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ID: 246290
2012
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Abstract
OBJECTIVE: The present study aims to determine whether once weekly supplementation of vitamin D and alendronate is efficient and safe for treatment of postmenopausal osteoporosis.
STUDY DESIGN: Group I (42 women with postmenopausal osteoporosis) received daily supplementation of calcium (1000 mg) and vitamin D (880 IU) while group II (42 women with postmenopausal osteoporosis) had weekly supplementation of vitamin D (2800 IU) along with weekly treatment of alendronate (70 mg).
RESULTS: Group I had significantly lower lumbar spine T-scores before and after treatment. Post-treatment lumbar spine T-scores and femur neck T-scores were significantly higher with respect to pre-treatment scores in both study groups. The alterations in lumbar spine and femur neck T-scores were statistically similar in both group I and group II.
CONCLUSION: Once weekly administration of vitamin D and alendronate is an effective and safe option of treatment for women who cannot take calcium supplements for postmenopausal osteoporosis.
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budak2012gormis
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| Authors | ;Mehmet Şükrü Budak;Sedat Akgöl;Şahin Önen;Selami Erdem;Serkan Kahyaoğlu;Mine Kanat Pektaş |
| Journal | journal of veterinary research |
| Year | 2012 |
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