the inhibitory effect of a lactobacillus acidophilus derived biosurfactant on serratia marcescens biofilm formation

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ID: 245033
2015
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Abstract
Objective(s):Serratia marcescens is one of the nosocomial pathogen. The ability to form biofilm is an important feature in the pathogenesis of S. marcescens. The aim of this study was to determine the anti-adhesive properties of a biosurfactant isolated from Lactobacillus acidophilus ATCC 4356, on S. marcescens strains. Materials and Methods: Lactobacillus acidophilus ATCC 4356, was selected as a probiotic strain to produce biosurfactant. Anti-adhesive activities was determined by pre-coating and co- incubating methods in 96-well culture plates. Results: The FTIR analysis of derived biosurfactant revealed the composition as protein component. Because of the release of such biosurfactants, L. acidophilus was able to interfere with the adhesion and biofilm formation of the S. marcescens strains. In co- incubation method this biosurfactant in 2.5 mg/ml concentration showed anti-adhesive activity against all tested strains of S. marcescens (P
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shokouhfard2015iranianthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Maliheh Shokouhfard;Rouha Kasra Kermanshahi;Roya Vahedi Shahandashti;Mohammad Mehdi Feizabadi;Shahram Teimourian
Journal PloS one
Year 2015
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