review: multimodal bioactive material approaches for wound healing
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ID: 244481
2018
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Abstract
Wound healing is a highly complex process of tissue repair that relies on the synergistic effect of a number of different cells, cytokines, enzymes, and growth factors. A deregulation in this process can lead to the formation of a non-healing chronic ulcer. Current treatment options, such as collagen wound dressings, are unable to meet the demand set by the wound environment. Therefore, a multifaceted bioactive dressing is needed to elicit a targeted affect. Wound healing strategies seek to develop a targeted effect through the delivery of a bioactive molecule to the wound by a hydrogel or a polymeric scaffold. This review examines current biomaterial and small molecule-based approaches that seek to develop a bioactive material for targeted wound therapy and accepted wound healing models for testing material efficacy.
| Reference Key |
mandla2018aplreview:
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|---|---|
| Authors | ;Serena Mandla;Locke Davenport Huyer;Milica Radisic |
| Journal | international journal of civil engineering and technology |
| Year | 2018 |
| DOI |
10.1063/1.5026773
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| URL | |
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