pericardial metastasis from p16 positive oropharyngeal squamous cell carcinoma
Clicks: 211
ID: 243823
2018
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Steady Performance
30.0
/100
211 views
20 readers
AI Quality Assessment
Not analyzed
Readership in this journal
SteadyRanked #14 of 23 articles by views in Clinical rheumatology
Most read
Least read
Bar heights use a square-root scale.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
Distant metastasis from head and neck cancers is a rare occurrence, especially in the case of HPV positive primaries, which are statistically less aggressive than HPV negative tumors. Our patient presented with a p16 positive oropharyngeal cancer, a surrogate marker for HPV. He underwent a laser pharyngectomy and radical neck dissection with adjuvant post-op radiation therapy. Approximately two years later our patient presented to hospital with an atypical presentation of cardiac tamponade. Pathology from tissue obtained at the time of a pericardial window was consistent with malignant squamous cell carcinoma of the pericardium. No local disease recurrence was found. Despite his low risk profile and the effective loco-regional control of his disease, he eventually succumbed to complications from distant metastasis. This is the first report of an HPV positive oropharyngeal primary with distant cardiac metastasis, to our knowledge. Considering the rarity of this outcome and the atypical presentation seen in our patient, we hope to use this report to raise awareness on the possibility of cardiac metastasis in head and neck cancer survivors presenting with non-specific or new cardiac signs/symptoms with unknown etiology.
| Reference Key |
kuta2018otolaryngologypericardial
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | ;Victoria Kuta;Matthew Rigby;Robert Hart;Jonathan Trites;S. Mark Taylor |
| Journal | Clinical rheumatology |
| Year | 2018 |
| DOI |
10.1016/j.xocr.2017.11.007
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.