synthesis of resorcinolic lipids bearing structural similarities to cytosporone a
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ID: 243589
2009
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Abstract
Inspired by the structure and biological activities of resorcinolic lipids and, particularly cytosporone A- a potent inhibitor of plantule germination and growth, we have performed the synthesis of the analogs 3-heptyl-3-hydroxy-5,7-dimethoxy-2-benzofuran-1(3H)-one (1) and 3-heptyl-3-hydroxy-4,6-dimethoxy-2-benzofuran-1(3H)-one (2). The intermediates and products were submitted to allelopathic test using Lactuca sativa L. seeds. Target compound 1 showed an inhibitory effect on germination and growth of hypocotyl and radicle in milimolar range.
| Reference Key |
santos2009qumicasynthesis
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|---|---|
| Authors | ;Edson dos Anjos dos Santos;Adilson Beatriz;Dênis Pires de Lima;Maria Rita Marques;Carla Braga Leite |
| Journal | greece and rome |
| Year | 2009 |
| DOI |
10.1590/S0100-40422009000700032
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| URL | |
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