hormone sensitivity of tumor in women with breast cancer

Clicks: 160
ID: 242917
2007
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Steady

Ranked #49 of 67 articles by views in İşletme araştırmaları dergisi

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Breast cancer is the most common malignant neoplasm in women. The presence of hormone receptors on malignant cells influences the prognosis and application of the appropriate therapy. The receptor status of estrogen and proestrogen was tested in relation to the age of the patients and clinical stage of disease. The analysis comprised 449 patients with breast cancer, mean age 56.2±12 years, treated at the Oncology Clinic CC Nis and operated at the Surgery Clinic CC Nis. The patients were divided into four groups: I group - 246 patients with ER+/PR+ receptors; II group - 45 patients with ER+/PR- receptors; III group - 20 patients with ER-/PR+ receptors and IV group - 109 patients with ER-/PR- receptors. The clinical stage of the tumor was described as operative, locally advanced and metastatic, plus patient age stratification. The receptor status was determined in 440 patients, while it remained unknown in 9(2%) cases. In regard to the total number of patients, ER+/PR+ was registered in 54.7% of the patients, ER+/PR- in 14.0%, ER-/PR+ in 4.5%, and ER-/PR- in 24.3% The most common one was a hormone-sensitive breast tumor (76%) compared to non-sensitive tumors (24%). Of hormone-sensitive tumors, the most common were Er+/Pr+ tumors in 58% of the patients, and the least common Er-/Pr+ tumors in 4%. In women younger than 40, hormonal non-sensitivity dominates (55%). Hormone-sensitive tumors are more present as the patients grow older, and they dominate in patients older than the age of 70. Operative tumor was found in 78.64% of the patients, locally advanced in 18.18%, and metastasis in 3.18%. Hormone-sensitive tumors are far more often operative and less locally advanced than non-sensitive tumors (Hi=8.2, p<0.01). Metastatic tumors did not show any significant difference in hormone sensitivity.
Reference Key
dimitrios2007actahormone Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Kontsmans Dimitrios;Dejan Ilic;Milos Krstic;Miljana Pavlovic;Ivana Pesic
Journal İşletme araştırmaları dergisi
Year 2007
DOI
DOI not found
URL
http://publisher.medfak.ni.ac.rs/2007-html/2-broj/HORMONE%20SENSITIVITY%20OF%20TUMOR....pdf
Keywords
Breast cancer estrogen proestrogenmedicine

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.