hormonal disorders as significant pathogenetic factor of acne in women

Clicks: 156
ID: 242518
2014
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Abstract
Objective: to investigatie the features of hormonal disorders in women with acne. Materials and Methods. The study involved 126 women with acne aged 19 to 43 years, average age 32.23 ± 0.81 years. In plasma of venous blood we determined levels of testosterone, dihydrotestosterone, dehydroepiandrosterone sulfate, 17-pregnenolone, anti-Mullerian hormone, thyrotropin, glycated hemoglobin. Sonography of pelvic organs and thyroid gland has been carried out. Results. It was found that acne in women occurs on a background of polycystic ovary syndrome — 27.77 %, atypical forms of congenital adrenal glands dysfunction — 22.12 %, hyperprolactinemia syndrome — 15.01 %, hypothyroidism — 6.32 %, diabetes mellitus type 2 — 6.32 %. Conclusions. Hormonal study of women with acne should include an assessment of the function of ovaries, adrenal glands, thyroid gland, determination of the level of prolactin in the blood plasma and glycated hemoglobin. Treatment should be aimed at management of hormonal and metabolic disorders, and topical treatment of acne. Before 30 years of age it is important to diagnose polycystic ovary syndrome and late forms of congenital dysfunction of the adrenal glands, after 30 — hyperprolactinemia syndrome, hypothyroidism, diabetes mellitus type 2, and after 40 years acne often manifests on the background of ovarian failure.
Reference Key
naumova2014mnarodnijhormonal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;L.O. Naumova
Journal Macromolecular rapid communications
Year 2014
DOI
10.22141/2224-0721.5.61.2014.76854
URL
http://iej.zaslavsky.com.ua/article/view/76854
Keywords
acne clinical endocrinology womendiseases of the endocrine glands

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