dynamic potential and surface morphology study of sertraline membrane sensors

Clicks: 262
ID: 242410
2015
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Abstract
New rapid, sensitive and simple electrometric method was developed to determine sertraline hydrochloride (Ser-Cl) in its pure raw material and pharmaceutical formulations. Membrane sensors based on heteropolyacids as ion associating material were prepared. Silicomolybdic acid (SMA), silicotungstic acid (STA) and phosphomolybdic acid (PMA) were used. The slope and limit of detection are 50.00, 60.00 and 53.24 mV/decade and 2.51, 5.62 and 4.85 μmol L−1 for Ser-ST, Ser-PM and Ser-SM membrane sensors, respectively. Linear range is 0.01–10.00 for the three sensors. These new sensors were used for the potentiometric titration of Ser-Cl using sodium tetraphenylborate as titrant. The surface morphologies of the prepared membranes with and without the modifier (ion-associate) were studied using scanning and atomic force microscopes.
Reference Key
khater2015journaldynamic Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;M.M. Khater;Y.M. Issa;H.B. Hassib;S.H. Mohammed
Journal reading & writing
Year 2015
DOI
10.1016/j.jare.2014.11.005
URL
http://www.sciencedirect.com/science/article/pii/S2090123214001386
Keywords
SEM sensors afm

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