clinical observation of oct on detecting the structural change of cornea and conjunctiva in patients with acute angle closure glaucoma

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2015
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Abstract
AIM:To observe thickness and morphological changes of cornea and bulbar conjunctiva pre- and post acute angle closure glaucoma(AACG)therapy by optical coherence tomography(OCT).

METHODS:Twenty-five patients with AACG were recruited. Intraocular pressure(IOP)and morphological characteristic of cornea and conjunctiva were measured at their first visit, 1, 2 and 3d after they began the treatments.

RESULTS:The corneal epithelium thickness and corneal thickness of patients with acute attack of angle closure glaucoma were 72.76±11.95μm and 589.40±66.91μm; the conjunctival epithelial layer thickness was 58.88±12.87μm; the thickness of conjunctive stroma was 299.76±94.86μm; the conjunctival full thickness was 358.64±102.55μm. The corneal epithelium thickness and corneal thickness at the first day of the treatment were 69.28±12.65μm and 579.04±67.88μm; the conjunctival epithelial layer thickness was 57.04±12.05μm; the thickness of conjunctive stroma was 282.44±91.47μm; the conjunctival full thickness was 339.48±100.28μm. the corneal epithelium thickness and corneal thickness at the second day of treatment were 66.76±11.42μm and 563.32±63.87μm; the conjunctival epithelial layer thickness was 54.76±11.01μm; the thickness of conjunctive stroma was 267.00±98.54μm; the conjunctival full thickness was 322.16±106.12μm. the corneal epithelium thickness and corneal thickness of the third day treatment are 65.16±12.25μm and 550.36±71.48μm; the conjunctival epithelial layer thickness was measured 53.36±10.29μm; the thickness of conjunctive stroma was 252.76±99.32μm; the conjunctival full thickness was 306.52±107.31μm. The difference of IOP, corneal epithelial thickness, corneal thickness, conjunctival epithelial layer thickness, conjunctival stroma thickness and conjunvtival full thickness had statistically significant(P<0.05).

CONCLUSION:The corneal and conjunctival thickness in patients at acute attack of angle closure glaucom increase. The edema level decreases with IOP.

Reference Key
zhao2015guojiclinical Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Li Zhao;Qing-Song Li;Xing-Ru Zhang
Journal journal of fungi
Year 2015
DOI
10.3980/j.issn.1672-5123.2015.11.26
URL
http://ies.ijo.cn/cn_publish/2015/11/201511026.pdf
Keywords
glaucoma cornea phacoemulsification

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