facial paralysis associated to hypothyroidism in a dog
paralisia facial associada a hipotireoidismo em um cão

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ID: 241771
2012
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Abstract
The hypothyroidism is the most commonly endocrinopathy in dogs, that occurs preferentially in middle-aged pure breed. The clinical signs associated with hypothyroidism are variable, many times non-specific, including metabolical, dermatological or cardiovascular. The main laboratorial findings are non-regenerative anemia and hypercholesterolemia. Hyponatremia, increase on alanine transferase and alkaline phosphatase activity also can be observed in a lower frequency. There are some reports of peripheral neuropathies caused by hypothyroidism, but the pathophysiology of this process is still unknown. There are specific diagnostic tests that can be used to help diagnose hypothyroidism, and those should be aligned together with the animal´s clinical symptoms. The thyroxine stimulating hormone, and free and total thyroxine concentrations are the most used tests. A Pit Bull dog, female, over weighted, was treated presenting left facial paralysis. Thyroid function tests confirmed hypothyroidism. The animal was treated with hormonal replacement and there was improvement in clinical signs in 40 days, confirming that hypothyroidism was facial paralysis’ cause.

O hipotireoidismo é a endocrinopatia mais comum em cães, que acomete preferencialmente animais de meia-idade de raça pura. Os sintomas clínicos são bastante variados, e muitas vezes inespecíficos, incluindo alterações metabólicas, dermatológicas ou cardiovasculares. Os principais achados laboratoriais são anemia arregenerativa e hipercolesterolemia. Hiponatremia, aumento da atividade da fosfatase alcalina e da alanina aminotransferase também podem ser observadas com menor frequência. Existem alguns relatos de neuropatias periféricas causadas por hipotireoidismo, mas a fisiopatologia deste processo é ainda desconhecida. Existem testes específicos, utilizados no auxílio ao diagnóstico do hipotireoidismo, que devem ser interpretados em conjunto com os sinais clínicos do animal. As concentrações de tireotopina (TSH), tiroxina (T4) livre e total são os testes hormonais mais utilizados. Uma cadela da raça Pit Bull, obesa, foi atendida apresentando paralisia facial esquerda. Os exames de função tireoideana confirmaram hipotireoidismo. O animal foi tratado com reposição hormonal e houve melhora dos sinais clínicos em um período de 40 dias, confirmando o hipotireoidismo como causa da paralisia facial.

Reference Key
machado2012semina:facial Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Luiz Henrique de Araújo Machado;Josyanne Christine Oshika;Mariana Isa Poci Palumbo;Felipe Gazza Romão
Journal frontiers in neuroendocrinology
Year 2012
DOI
10.5433/1679-0359.2012v33n1p351
URL
http://www.uel.br/revistas/uel/index.php/semagrarias/article/view/6357
Keywords
Agriculture (General) obesidade tiroxina

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