klymollins t–x, bioactive eunicellin-based diterpenoids from the soft coral klyxum molle
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ID: 241608
2014
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Abstract
Five new eunicellin-based diterpenoids, klymollins T–X (1–5), along with two known compounds (6 and 7) have been isolated from the soft coral Klyxum molle. The structures of these new metabolites were elucidated by extensive spectroscopic analysis and by comparison with related known compounds. Compound 5 was found to exert significant in vitro anti-inflammatory activity against LPS-stimulated RAW264.7 macrophage cells. Furthermore, compounds 4 and 7 were shown to exhibit cytotoxicity against a limited panel of human cancer cell lines.
| Reference Key |
chang2014marineklymollins
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|---|---|
| Authors | ;Fang-Yu Chang;Fang-Jung Hsu;Chi-Jen Tai;Wen-Chi Wei;Ning-Sun Yang;Jyh-Horng Sheu |
| Journal | jixie gongcheng xuebao/journal of mechanical engineering |
| Year | 2014 |
| DOI |
10.3390/md12053060
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| URL | |
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