estudo epidemiológico da febre purpúrica brasileira: epidemia em localidade do estado de são paulo (brasil), 1986 brazilian purpuric fever: an epidemiological study of an outbreak in the locality of the s. paulo state, brazil, in 1986
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ID: 240723
1991
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Abstract
Estudou-se um surto de febre purpúrica brasileira ocorrido em Serrana, SP (Brasil) em 1986 e sua associação com conjuntivite purulenta, aglomeração e sintomas respiratórios. Foi adotado o modelo de estudo, caso-controle. Chamou-se caso confirmado o paciente que satisfizesse um conjunto de critérios tendo "score" maior ou igual a 12 pontos, e caso suspeito "score" entre 8 e 12 (o "score" foi efetuado usando-se o seguinte critério: ocorrência de febre, igual a 5 pontos; diarréia e/ou vômitos igual a 1; fenômenos hemorrágicos igual a 3; plaquetopenia e/ou leucopenia igual a 3; hemocultura e/ou líquor e/ou cultura de orofaringe positiva para Haemophylus aegyptius igual a 7; síndrome de Waterhouse Friedrichsen igual a 7). Tomou-se como controle crianças com "score" menor do que 5. O controle foi pareado com o caso segundo as variáveis idade, sexo e condição sócio-econômica. Levantaram-se informações sobre 14 casos confirmados, 38 suspeitos e 78 controles. Concluiu-se que a febre purpúrica brasileira apresentou forte associação com conjuntivite purulenta pregressa e/ou atual; parece haver associação entre aglomeração e febre purpúrica e que os sintomas respiratórios como tosse e/ou coriza não estão a ela associados, pelo menos na população estudada.
A case control model was used in the study of an outbreak of Brazilian purpuric fever BPF which occurred in Serrana, S. Paulo State, Brazil, in 1986. Three hypotheses were raised: 1 - purulent conjunctivitis is associated with BPF; 2 - a cluster effect accurs in BPF; 3 - respiratory symptoms may be a variation of the clinical picture of the disease. Numerical values were attributed to different findings, as follows: fever = 5; diarrhea and/or vomiting = 1; haemorrhagic findings = 3; thrombocytopenia and/or leukopenia = 3; Haemophilus aegyptius positive hemoculture and/or Haemophilus aegyptius positive cerebrospinal fluid culture and/or H. a. oropharynx culture = 7; Waterhouse Friedrichsen syndrome = 7. Those cases for which the sum total of points reached or exceeded 13 were considered as confirmed and those obtaining between 8 and 12 were considered as suspect. Children with a score below 5 were taken as control cases. Cases and controls were matched according to sex, age and socioeconomic level. The total groups studied included 14 confirmed cases, 38 suspect cases and 78 controls. It was concluded that purpuric fever is strongly associated with previous and/or present purulent conjunctivities; a cluster effect seems to occur; respiratory symptoms such as coughing and/or coryza were not associated with BPF.
A case control model was used in the study of an outbreak of Brazilian purpuric fever BPF which occurred in Serrana, S. Paulo State, Brazil, in 1986. Three hypotheses were raised: 1 - purulent conjunctivitis is associated with BPF; 2 - a cluster effect accurs in BPF; 3 - respiratory symptoms may be a variation of the clinical picture of the disease. Numerical values were attributed to different findings, as follows: fever = 5; diarrhea and/or vomiting = 1; haemorrhagic findings = 3; thrombocytopenia and/or leukopenia = 3; Haemophilus aegyptius positive hemoculture and/or Haemophilus aegyptius positive cerebrospinal fluid culture and/or H. a. oropharynx culture = 7; Waterhouse Friedrichsen syndrome = 7. Those cases for which the sum total of points reached or exceeded 13 were considered as confirmed and those obtaining between 8 and 12 were considered as suspect. Children with a score below 5 were taken as control cases. Cases and controls were matched according to sex, age and socioeconomic level. The total groups studied included 14 confirmed cases, 38 suspect cases and 78 controls. It was concluded that purpuric fever is strongly associated with previous and/or present purulent conjunctivities; a cluster effect seems to occur; respiratory symptoms such as coughing and/or coryza were not associated with BPF.
| Reference Key |
kerr-pontes1991revistaestudo
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| Authors | ;Ligia R.S. Kerr-Pontes;Antonio Ruffino-Netto |
| Journal | proceedings - 2016 3rd international conference on information technology, computer, and electrical engineering, icitacee 2016 |
| Year | 1991 |
| DOI |
10.1590/S0034-89101991000500009
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| URL | |
| Keywords | Keywords not found |
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