synthesis of substituted 1,4-diazepines and 1,5-benzodiazepines using an efficient heteropolyacid-catalyzed procedure
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ID: 240529
2010
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Abstract
An efficient and improved procedure for the synthesis of 1,4-diazepine and 1,5-benzodiazepine derivatives via the reaction of ketimine intermediates with aldehydes in the presence of Keggin-type heteropolyacids (HPAs) was developed. High yields and short reaction times were obtained for both electron-releasing and electron-withdrawing substituted 1,4-diazepine and 1,5-benzodiazepines derivatives.
| Reference Key |
benadji2010moleculessynthesis
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|---|---|
| Authors | ;Sihame Benadji;Cherifa Rabia;Norah Bennamane;Saliha Bakhta;Rachedine Kaoua;Bellara Nedjar-Kolli |
| Journal | Journal of ethnopharmacology |
| Year | 2010 |
| DOI |
10.3390/molecules16010092
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| URL | |
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