profound hypoglycemia with ecstasy intoxication

Clicks: 179
ID: 239665
2015
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Abstract
Background. 3,4-Methylenedioxymethamphetamine (MDMA) or ecstasy is a synthetic drug that is commonly abused for its stimulant and euphoric effects. Adverse MDMA effects include hyperthermia, psychomotor agitation, hemodynamic compromise, renal failure, hyponatremia, and coma. However, endogenous hyperinsulinemia with severe persistent hypoglycemia has not been reported with MDMA use. Case Report. We report the case of a 29-year-old woman who remained severely hypoglycemic requiring continuous intravenous infusion of high-dose dextrose solutions for more than 24 hours after MDMA intoxication. Serum insulin and C-peptide levels confirmed marked endogenous hyperinsulinemia as the cause of the severe hypoglycemia. Why Should an Emergency Physician Be Aware of This? Immediate and frequent monitoring of blood glucose should be instituted in patients presenting with MDMA ingestion particularly if found to be initially hypoglycemic. Early recognition can help prevent the deleterious effects of untreated hypoglycemia that can add to the morbidity from MDMA use. Clinicians need to be aware of this side effect of MDMA so they can carefully monitor and treat it, especially in patients presenting with altered mental status.
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carrera2015caseprofound Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Perliveh Carrera;Vivek N. Iyer
Journal Ecology letters
Year 2015
DOI
10.1155/2015/483153
URL
http://dx.doi.org/10.1155/2015/483153
Keywords
critical care first aid intensive care medical emergencies

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