a design method for fes bone health therapy in sci

Clicks: 192
ID: 238816
2016
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Abstract
FES assisted activities such as standing, walking, cycling and rowing induce forces within the leg bones and have been proposed to reduce osteoporosis in spinal cord injury (SCI). However, details of the applied mechanical stimulus for osteogenesis is often not reported. Typically, comparisons of bone density results are made after costly and time consuming clinical trials. These studies have produced inconsistent results and are subject to sample size variations. Here we propose a design process that may be used to predict the clinical outcome based on biomechanical simulation and mechano-biology. This method may allow candidate therapies to be optimized and quantitatively compared. To illustrate the approach we have used data obtained from a rower with complete paraplegia using the RowStim (III) system.
Reference Key
andrews2016europeana Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Brian Andrews;James Shippen;Monica Armengol;Robin Gibbons;William Holderbaum;William Harwin
Journal journal of applied mathematics
Year 2016
DOI
10.4081/ejtm.2016.6419
URL
http://www.pagepressjournals.org/index.php/bam/article/view/6419
Keywords
osteoporosis spinal cord injury

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