von willebrand's disease in the german shepherd dog : clinical communication

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ID: 238602
2000
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Ranked #98 of 123 articles by views in race: revista de administração, contabilidade e economia

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Abstract
Two litters of Germanshepherd dogs were evaluated for a haemorrhagic tendency that was characterised by excessive bleeding from the umbilicus at birth, haemorrhage and haematoma formation at vaccination, excessive bruising, and lameness due to haemarthrosis. Platelet counts, clotting times and Von Willebrand's factor (VWF) assays were assessed in all dogs. Factor VIII determination was performed in 1 puppy and its parents. Based on the clotting times and VWF assay, 6 puppies (4 male and 2 female) showed type I Von Willebrand's disease (VWD), 5 (4 male and 1 female) possible type II VWD, and 4 were unaffected. One puppy with possible type II VWD had very low factor VIII activity; its sire had a normal factor activity, whereas the dam was in the low-normal range. This article reports type I and possible type II VWD in 2 related litters of German shepherd dogs, the latter being rare in German shepherd dogs.
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lobetti2000journalvon Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;R.G. Lobetti;T. Dippenaar
Journal race: revista de administração, contabilidade e economia
Year 2000
DOI
10.4102/jsava.v71i2.693
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