aspergillus nidulans pmts form heterodimers in all pairwise combinations

Clicks: 232
ID: 235514
2014
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Abstract
Eukaryotic protein O-mannosyltransferases (Pmts) are divided into three subfamilies (Pmt1, Pmt2, and Pmt4) and activity of Pmts in yeasts and animals requires assembly into complexes. In Saccharomyces cerevisiae, Pmt1 and Pmt2 form a heteromeric complex and Pmt 4 forms a homomeric complex. The filamentous fungus Aspergillus nidulans has three Pmts: PmtA (subfamily 2), PmtB (subfamily 1), and PmtC (subfamily 4). In this study we show that A. nidulans Pmts form heteromeric complexes in all possible pairwise combinations and that PmtC forms homomeric complexes. We also show that MsbA, an ortholog of a Pmt4-modified protein, is not modified by PmtC.
Reference Key
kriangkripipat2014febsaspergillus Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Thanyanuch Kriangkripipat;Michelle Momany
Journal journal of ayub medical college, abbottabad : jamc
Year 2014
DOI
10.1016/j.fob.2014.03.006
URL
http://www.sciencedirect.com/science/article/pii/S2211546314000291
Keywords
aspergillus nidulans pmtbiology (general)

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