investigating the immunizing effect of the rubella epidemic in japan, 2012-14

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ID: 232690
2015
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Abstract
Objectives: A rubella epidemic occurred in Japan from 2012-14, involving more than 15,000 cases. The present study aimed to estimate the immunizing effect of the epidemic, analyzing seroepidemiological data that were collected over time and age. Methods: Annual nationwide cross-sectional surveys were conducted from July to September, collecting serum from at least 5,400 individuals. The proportions seropositive were estimated before (2012), during (2013) and after (2014) the epidemic. Results: While the cases were mainly seen among men aged from 30-49 years, no significant increase was observed in the proportion seropositive in the corresponding age group. Even after the epidemic, age-standardized proportion seropositive of the total population remained 79.3% (95% confidence interval (CI): 75.2, 83.4) and that among males was as small as 76.7% (95% CI: 73.8, 79.6). Conclusions: Susceptible pockets remain in Japan, exposing the country to risk of additional rubella epidemics.
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nishiura2015internationalinvestigating Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Hiroshi Nishiura;Ryo Kinoshita;Yuichiro Miyamatsu;Kenji Mizumoto
Journal israel journal of chemistry
Year 2015
DOI
10.1016/j.ijid.2015.07.006
URL
http://www.sciencedirect.com/science/article/pii/S1201971215001733
Keywords
vaccination epidemic seroepidemiologic studies

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