treatment of choroidal neovascularisation in highly myopic eyes
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2012
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Abstract
Background: The aim of this study was to examine
the effectiveness (visual outcome) of photodynamic
therapy with verteporfin (PDT) and
intravitreal anti-VEGF therapy for the treatment
of choroidal neovascularisation secondary to
pathologic myopia.
Methods: A retrospective study of choroidal
neovascularisation in highly myopic patients
was undertaken at the Eye Hospital Ljubljana
(from 2004 to 2010). The main outcome measures
were: spherical equivalent, age at onset of
CNV, composition and location of CNV, visual
acuity before treatment, treatment type (PDT,
intravitreal anti-VEGF injections, combination
of both treatments), visual acuity after treatment
and treatment-related complications.
Results: Fifty-nine eyes of 59 patients (7 men
and 52 women) with myopic CNV were enrolled
in the study. The mean age of the patients was
59.7 (range 26–83) years and the spherical equivalent
refractive error was – 10.2 D (range – 6.0 D
to – 20.0 D). Twenty-four eyes were treated with
PDT, 9 with PDT and anti-VEGF, and 26 eyes
with anti-VEGF injections alone. The followup
period was 21.5 months (range 6 months–6
years). The patients treated with anti-VEGF injections
had a better final best-corrected visual
acuity than PDT treated patients. No systemic
side effects were noted.
Conclusions: Intravitreal anti-VEGF injections
are an effective therapy for sub- and juxtafoveal
myopic CNV.
| Reference Key |
lavri2012zdravnikitreatment
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|---|---|
| Authors | ;Alenka Lavrič;Mojca Urbančič;Aleksandra Kraut;Davorin Sevšek;Polona Jaki Mekjavić |
| Journal | planta medica |
| Year | 2012 |
| DOI |
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| URL | |
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