gastrointestinal biopsy in henoch-schönlein purpura: a great diagnostic contribution

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2017
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Abstract
Henoch-Schönlein purpura is an IgA-mediated immune vasculitis which is characterized by purpuric lesions and osteoarticular, intestinal and sometimes renal manifestations. The histopathological substrate of this entity is leucocytoclastic vasculitis (LCV) with IgA deposits seen on immunohistochemistry. We here report the case of a 27-year-old woman with abdominal pain and cutaneous purpura. Upper and lower endoscopic exploration showed purpuric lesions in the rectum but not in the stomach. Skin biopsy revealed LCV. IgA deposits were seen only in gastric mucosa. The patient was treated with corticoids which led to improvement of both the cutaneous and digestive symptoms. This case suggests that gastrointestinal biopsies of both normal and abnormal mucosa should be taken in Henoch-Schönlein purpura, especially in patients with atypical forms.
Reference Key
akkari2017europeangastrointestinal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Imen Akkari;Soumaya Mrabet;Elhem Ben Jazia
Journal indian journal of dental research
Year 2017
DOI
10.12890/2017_000662
URL
http://www.ejcrim.com/index.php/EJCRIM/article/view/662
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